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Swelling of the parotid gland may be due to calculi in the parotid ducts, tumors or cysts, or to a reaction to iodides Other causes include starch ingestion, sarcoidosis, cirrhosis, diabetes, bulimia, pilocarpine use for dry mouth, and Sj gren s syndrome Parotitis may also be produced by pyogenic organisms (eg, S aureus, gram-negative organisms), particularly in debilitated individuals with poor oral intake, drug reaction (phenothiazines, propylthiouracil), and other viruses (influenza A, parainfluenza, EBV infection, coxsackieviruses, adenoviruses, HHV-6) Swelling of the parotid gland must be differentiated from inflammation of the lymph nodes located more posteriorly and inferiorly than the parotid gland
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Parotid tenderness and overlying facial edema are the most common physical findings Usually, one parotid gland enlarges
Other manifestations of the disease are less common than inflammation of the salivary glands These usually follow the
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parotitis but may precede it or occur without salivary gland involvement and include meningitis (30%), orchitis (on rare occasion leads to priapism or testicular infarction), pancreatitis (usually mild), oophoritis, thyroiditis, neuritis, hepatitis, myocarditis, thrombocytopenia, migratory arthralgias (noted infrequently among adults and rarely in children), and nephritis Mumps has also been associated with cases of endocardial fibroelastosis Rare neurologic complications include encephalitis, Guillain Barr syndrome, cerebellar ataxia, facial palsy, and transverse myelitis Encephalitis is associated with cerebral edema, serious neurologic manifestations, and sometimes death Deafness develops from eighth nerve neuritis and data from Japan suggest it occurs in about 03% of patients
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Bonnet MC et al Mumps vaccine virus strains and aseptic meningitis Vaccine 2006 Nov 30;24(49 50):7037 45 [PMID: 16884835] Centers for Disease Control and Prevention (CDC) Brief report: update: mumps activity United States, January 1 October 7, 2006 MMWR Morb Mortal Wkly Rep 2006 Oct 27;55(42):1152 3 [PMID: 17065981] Davidkin I et al Etiology of mumps-like illnesses in children and adolescents vaccinated for measles, mumps, and rubella J Infect Dis 2005 Mar 1;191(5):719 23 [PMID: 15688285] Harling R et al The effectiveness of the mumps component of the MMR vaccine: a case control study Vaccine 2005 Jul 1;23(31):4070 4 [PMID: 15950329]
Mumps live virus vaccine is safe and highly effective It is recommended for routine immunization for children over age 1 year, either alone or in combination with other virus vaccines (eg, in MMR vaccine or as a quadrivalent vaccine with varicella) A second dose is recommended for children (ages 4 6 years) before starting school The current mumps strain (Jeryl Lynn) has the lowest associated incidence of postvaccine aseptic meningitis (from 1 in 150,000 to 1 in 18 million) There are no known cases of long-term sequelae associated with mumps vaccination Reactions are reviewed in the measles section It should not be given to pregnant women or to immunocompromised individuals, though the vaccine has been given to asymptomatic HIV-infected individuals without adverse sequelae Mumps vaccine markedly decreased the incidence of mumps in the United States and in the United Kingdom Persons in whom mumps develops are less likely to have received a second vaccine dose The mumps skin tests are less reliable than serum neutralization titers in determining immunity
Use a forever loop to indicate that the normal case is to continue the loop indefinitely; for example, if your program is waiting for an event to occur somewhere in the system. The conditions for breaking out of the loop would then be exceptional and managed inside the body of the loop. Although it is possible to use a forever loop to good effect, Example 5-20 is a degenerate case. The initialization, increment, and test would be done more cleanly in the header of the for loop, and the program would then be easier to understand. It is shown here to illustrate that a forever loop is possible.
Incubation period 9 12 days from exposure Muscle weakness, headache, stiff neck, fever, nausea and vomiting, sore throat Lower motor neuron lesion (flaccid paralysis) with decreased deep tendon reflexes and muscle wasting Cerebrospinal fluid shows excess leukocytes, with lymphocytic predominance; count is rarely more than 500/mcL
The patient should be isolated until swelling subsides (about 9 days from symptom onset) and kept at bed rest during the febrile period Treatment is symptomatic as needed Topical application of warm or cold compresses may relieve parotid discomfort
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