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Boeckh M et al Emerging viral infections after hematopoietic cell transplantation Pediatr Transplant 2005 Dec;9 Suppl 7:48 54 [PMID: 16305617] Caserta MT et al Human herpesvirus 6 Clin Infect Dis 2001 Sep 15;33(6):829 33 [PMID: 11512088] Dewhurst S Human herpesvirus type 6 and human herpesvirus type 7 infections of the central nervous system Herpes 2004 Jun;11 Suppl 2:105A 111A [PMID: 15319097]

First-line therapy against CMV infections is ganciclovir, 5 mg/kg intravenously every 12 hours for 14 21 days Due to potential toxicities, foscarnet (loading with 90 mg/kg intravenously, followed by 60 mg/kg every 8 hours over weeks) and cidofovir (5 mg/kg intravenously every week for 2 weeks) are usually reserved for CMV infections that are resistant to ganciclovir A daily maintenance regimen using both ganciclovir (375 mg/kg intravenously) and foscarnet (60 mg/kg intravenously), each over 1 hour, has been shown to be safe and effective in treating clinically resistant CMV retinitis, although it is less effective in controlling ganciclovir-susceptible CMV viremia Cidofovir is given only every 2 weeks, 375 mg intravenously, for maintenance Oral valganciclovir (900 mg daily) is replacing oral ganciclovir for maintenance and for prophylactic therapy among persons who have undergone solid organ or bone marrow transplantation Transplant recipients do not benefit from combined foscarnet and ganciclovir preemptive therapy Dosage adjustments of all medications are needed for renal impairment Adoptive immunotherapy with polyclonal CMV-specific T cells is a new modality of therapy for infections in the allogeneic bone marrow transplant population that may obviate the need for antivirals in the future In pregnant women with primary CMV infection, passive immunization with hyperimmune globulin appears preliminarily to be efficacious in both treatment and prevention of fetal infection, but controlled clinical trials are needed for confirmation A sustained-release ganciclovir implant controls disease in the implanted eye (but not elsewhere) more effectively than intravenous ganciclovir The role of HAART in reducing the need for CMV antivirals is primary Fomivirsen is an intravitreal agent active against CMV strains that are resistant to ganciclovir, foscarnet, and cidofovir Adjuvant filgrastim may be useful in managing the neutropenia associated with ganciclovir and its analogues

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Biron KK Antiviral drugs for cytomegalovirus diseases Antiviral Res 2006 Sep;71(2 3):154 63 [PMID: 16765457] Griffiths PD CMV as a cofactor enhancing progression of AIDS J Clin Virol 2006 Apr;35(4):489 92 [PMID: 16413825] Kalil AC et al Meta-analysis: the efficacy of strategies to prevent organ disease by cytomegalovirus in solid organ transplant recipients Ann Intern Med 2005 Dec 20;143(12):870 80 [PMID: 16365468]

who received live measles vaccine before age 12 months and as a result developed hypersensitivity rather than protective immunity When persons are infected later with wild measles virus, a potentially fatal illness may develop, with high fever; unusual rashes (papular, hemorrhagic), most prominent on the extremities, without Koplik s spots; headache; arthralgias; hepatitis; and a high rate of pneumonitis, occasionally with pleural effusions; followed by the appearance of extremely high measles antibody titers Measles may occur in HIV-infected individuals in an uncharacteristic fashion, with higher rates of pneumonitis, higher mortality, and prolonged viral shedding Vaccine failure rates, both primary and secondary, are higher in HIVinfected children The frequent difficulty in establishing a diagnosis suggests that measles may be more prevalent in epidemics than heretofore recognized Measles during pregnancy is not known to cause congenital abnormalities of the fetus However, it is associated with spontaneous abortion and premature delivery Measles in the offspring of mothers with measles ranges from mild to severe; therefore, it is recommended that infants born to such mothers be passively immunized with immunoglobulin at birth

Table 7.7 The names of the interface components Item Process To Track Number Of Samples To Acquire Wait Between Samples (Secs): Data To Plot menu (NSPopupButton) Start, Plot, View, List Status field process samples sleepsecs datatoplot Name

Prodrome of fever, coryza, cough, conjunctivitis, malaise, irritability, photophobia, Koplik s spots Rash: brick-red, irregular, maculopapular; onset 3 4 days after onset of prodrome; begins on the face and proceeds downward and outward, affecting the palms and soles last Leukopenia

You can also create a forever loop with a while(true) loop:

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