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not regulated for purposes of acid excretion Figure 9 4 illustrates the sequence of events that achieves hydrogen ion excretion on filtered phosphate and the addition of new bicarbonate to the blood The process of hydrogen ion secretion in this sequence is exactly the same as described previously, but the secreted hydrogen ion combines with filtered phosphate rather than with filtered bicarbonate Therefore, the bicarbonate generated within the tubular cell (that always occurs when hydrogen ions are secreted) enters the plasma and constitutes a net gain of bicarbonate by the blood, not merely a replacement for filtered bicarbonate Thus, when a secreted hydrogen ion combines in the lumen with a filtered buffer other than bicarbonate, the overall effect is not merely bicarbonate conservation but rather addition to the blood of new bicarbonate, which raises the bicarbonate concentration of the blood and the pH to a value similar to what it was before the addition of fixed acids Figure 9 4 also illustrates a point we want to emphasize: namely, that the renal contribution of new bicarbonate to the blood is accompanied by the excretion of an equivalent amount of buffered hydrogen ion in the urine In this case, in contrast to the reabsorption of bicarbonate, the secreted hydrogen ion remains in the tubular fluid, trapped there by the buffer, and is excreted in the urine This should reinforce the concept that bicarbonate can always be generated from CO2 and water, but to add this new bicarbonate to the blood (and alkalinize the blood), the kidneys must separate the hydrogen ion from the bicarbonate and excrete the hydrogen ion that is created at the same time

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Objectives for the project should be quantified, if possible, in terms of the following area(s): Cost savings Examples: reducing the costs to service a customer; or to retain customers; or to acquire customers; or to distribute products Service enhancements Examples: tighter scheduling windows for performing services or having the right information available in realtime while meeting with the customer Revenue generation opportunities Examples: being able to reach new markets with new products or services; cross-selling existing customers with new products or services; or stealing market share by offering an innovative product or service

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Another interesting example was quarterback Bart Starr, who couldn t perform under my father s standard tactic of semi-public humiliation, whether on the field or in the locker room One day, after being yelled at by my father for throwing an interception during practice, Starr asked for a closed-door meeting with Lombardi The young quarterback bravely made the point that if he was expected to lead the team on the field, he couldn t afford to be undercut by Lombardi s sometimes harsh criticisms in front of the team Lombardi agreed with this reasoning (no doubt also taking the measure of this quiet young man from a military family) and agreed not to criticize him in front of his teammates again Lombardi kept his end of the bargain, and from that day forward, the Lombardi Starr combination was enormously effective My father s handling of his next star quarterback, Sonny Jurgensen of the Redskins, was equally revealing of his motivational/inspirational techniques Jurgensen, a supremely talented athlete, had a reputation as a playboy who knew how to enjoy himself off the field (Some of his teammates later said that the legend far outstripped the fact, but Jurgensen himself enjoyed fueling the legend) I think it s safe to assume that Jurgensen was anxious about his first meeting with his new coach: The legendary rounder Jurgensen meets the equally legendary disciplinarian Lombardi! I walked into his office in Washington not knowing what to expect, Jurgensen later recalled After we shook hands, he

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Dim stamper As New PdfStamper(reader, New FileStream( "C:\Users\ dharmendra\Desktop\test1. pdf " , FileMode.Create), PdfWriter.

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form) that has been filtered and not reabsorbed reaches the collecting tubule, where it combines with secreted hydrogen ions to form monovalent phosphate (acid form) and is then excreted in the urine The bicarbonate entering the blood is new bicarbonate, not merely a replacement for filtered bicarbonate ATP, adenosine triphosphate

W H AT I T TA K E S T O B E # 1

regulation of hydrogen ion balanCe / 169

The current business processes should be understood and examined in detail, not on paper but in real-life situations The most effective way of documenting is by joining the mobile workers as they go about their day-to-day business During this documentation period, the system designers should determine: What information the user needs access to during the day including the complete inbound and outbound data flow; How the user currently gains access to information; Who needs to communicate and to whom, and how often; Which tasks are duplicated or done manually by in-house administrative workers on the behalf of mobile workers; What is the environment in which mobile workers operate (indoor/outdoor, rural/urban, etc); Which resources will help the mobile worker better accomplish his/her job; Incremental revenue opportunities by performing services/sales at that point of customer contact; What information are customers/clients looking for; Problems encountered when communicating/working when mobile; What other devices, equipment, hard copy data, etc, the mobile worker now carries to perform his/her tasks This is just a starting list, which should be customized according to your specific business