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The industrial importance of lamentous fungi is illustrated by applications ranging across the production of antibiotics, organic acids, proteins, and food. The best known examples of the use of lamentous fungi are for production of penicillin by Penicillium chrysogenum, citric acid by Aspergillus niger, and recombinant proteins by A. oryzae. However, during the last two decades, lamentous fungi have been used increasingly as eukaryotic hosts for foreign gene expression, for which they have several attractions (Jeenes et al., 1991). First, due to their saprophytic life they are capable of secreting large quantities of proteins (van Brunt, 1986). Posttranscriptional modi cations of proteins such as glycosylation are important capabilities offered by these hosts (Mackenzie et al., 1993). In addition, many species are generally regarded as safe by regulatory authorities. Despite the widespread industrial use and potential of fungal strains for secondary metabolite, organic acid, and heterologous protein production, relatively little is known about the in uence of engineering variables such as agitation conditions upon the morphology of such organisms in submerged cultures. In many fungal fermentations, the high apparent viscosities and the non-Newtonian behavior of the broths necessitate the use of high agitation speeds to provide adequate mixing

The energy scale (horizontal axis) can be calibrated in absolute terms by using a radionuclide whose photon energy is well known; usually one with a simple decay scheme. The most prominent peak, seen as a high point in the spectrum, is then assigned the energy value corresponding to the known energy of the principal gamma ray of the radionuclide under observation.

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This is a good time to consider the pros and cons of implementing backflushing, but with the knowledge that it may not be applicable to a company s specific circumstances The last step is to review the need for a document imaging system in order to layer more information onto the inventory database..

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The process of simplifying your code isn t as simple as it seems That may be a great one-line jest, but it s nonetheless true A single line of code capable of replacing (and performing the same function as) half a page of code is obviously more powerful In addition, the resulting solution is cleaner, simpler, easier to maintain and easier to use Once you ve taken the trouble to comprehend how and why the single line of code works, the solution containing it becomes easier to read and understand than the solution containing more verbose code I doubt that the argument that longer code is preferable because it s more explicit or easier to understand is ever more than a rationalization One way you can view the concept of simplicity is in terms of elements The elements are powerful.

} $year = $today[year]; $mysqlCommand = mysqldump --opt -h %s -u %s -p%s %s ; $gzipCommand = gzip > %s/%s-%s-%s-%s.gz ; $run_command = sprintf($mysqlCommand . | . $gzipCommand, $host, $user, $pass, $db, $backupdir, $db, $month, $day, $year); system($run_command); >

When you reduce your solution to its elemental properties, you remove extraneous and verbose material and invest a great deal in the remaining essentials Mature computer applications such as FileMaker are inherently complex, permitting myriad paths toward any goal you identify Your challenge is to find or create simplicity and harmony among the burgeoning complexity If you succeed, your code and the solutions it supports will be powerful and elegant as well as robust and scalable The following general principles govern the achievement of simplicity in solution development: n Simplicity doesn t simply happen In fact, if you have anything more than a shopping list to design, simplicity is frequently harder to achieve than complexity Moreover, arriving at a set of simple principles requires a more profound understanding of both the solution requirements and the development environment.

Browser targeting is another site management innovation from Dreamweaver. One of the major steps in any site development project is to test the Web pages in various browsers to look for inconsistencies and invalid code. Dreamweaver s Browser Targeting function enables you to check your HTML against any existing browser s profile. Dreamweaver includes predefined profiles for several browsers, and you can create a profile for any browser you d like to check.

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