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the latter case, a liquid phase may coat the particle and be attached by noncovalent, physical attraction. This type of system is called liquid liquid phase chromatography. A good example of liquid liquid phase chromatography is silica coated with a nonpolar hydrocarbon (e.g. C-18 reverse phase chromatography; Section 2.4.3). Commonly, the particles are composed of hydrated polymers such as cellulose or agarose. Such particles may be immobilized in a column (Section 2.3.1) and washed with mobile phase. They offer good ow characteristics and possess suf cient mechanical strength and chemical inertness for the chromatography of biomolecules. Because biomolecules have evolved to function in an aqueous environment, it is usually necessary to use aqueous buffers as the mobile phase if we require the molecule to retain its native structure (e.g. in the puri cation of active enzymes). If the native structure is not required, however, then it is possible to use more nonbiological conditions such as organic solvents (e.g. in puri cation of peptides by reverse phase chromatography; Section 2.4.3). Liquid solid or liquid liquid phases are the most common phase systems used in biochemistry. However, in specialized situations other phases may be used. For example, gas-solid and gas-liquid phases are used in gas chromatography (GC; Section 2.1.4). Regardless of the precise phase composition, chromatographic separation is a direct result of the different K values of each sample component. 2.1.3

gypsum and plate glass. These curves relate exposure rate actually expressed in dose units per mA min at 1 m for different kVp x-ray beams and for variations in shield thickness. Similar curves exist for other media and for higher energy special-purpose x-ray units such as those used in cancer therapy and testing of materials (see NCRP Report 49, 1988). These curves can be used to determine exposure versus shield thickness as shown in Example 15-7.

which, in terms of the forces, is (6.111) We remind the reader that in these equations we are talking about the average fields and average forces. In an equivalent fashion, we can show that ec-aB, = ar ec aB, ---=-=r ae

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Several approaches were used to model risks quantitatively. The models generated quantitative measures of the level of risk associated with the main options for mine waste management. Results were presented in a variety of ways for the board and other stakeholders, in a way that provided as much information as possible and demonstrated the variability in the outcomes. The aim was to provide results that could be understood readily, without either over-simplifying or over-complicating them. Figure 18.14 shows an example from an early run of the model, demonstrating that the Dredge option has the lowest risk cost at any specified level of confidence. Figure 18.15 shows another representation of the costs of the risks that might arise with each option, compared with their fixed or base costs, using different methods for analysing and estimating risk. As noted earlier, the OTML Board was concerned to ensure the risk management was adequate and transparent, and could be justified to the wide range of key stakeholders. The overall process provided outcomes that were valuable for the board, management and shareholders in determining the most appropriate course of action, given the complexity and constraints in the operating environment. The audit report confirmed this. More details are provided on the Ok Tedi website, www.OkTedi.com (search for risk), and in Bowden, Lane and Martin (2001).

2. Choose File Save As. The Save Drawing As dialog box opens. 3. In the File Name text box, change the filename to ab02-01.dwg. Choose your AutoCAD Bible folder and click Save. 4. At the bottom of the drawing area, click the Model tab. (If your screen doesn t show this tab, on the status bar, at the right end of the row of buttons, click the second to last button; its tooltip reads Model.) 5. From the Layer Control drop-down list on the Layers toolbar, choose the DETAILING layer. 6. Choose Rectangle from the Draw toolbar. (If the Draw toolbar is not displayed, rightclick any toolbar and choose Draw.) Follow the prompts, entering the text in the Dynamic Input tooltip:

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