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Soluble intracellular receptors include the steroid hormone receptors (estrogen, progesterone and cortisol), vitamin D receptor, thyroid hormone receptor, and retinoic acid receptor. Because of their insolubility in water, these hormones are transported in the blood by specific binding proteins. They dissociate from the binding protein, cross the membrane, and find their receptor. Hormones that diffuse across the membrane and enter the cell bind to soluble intracellular receptors. The central event for a receptor involves activation getting some new activity when the signal is present (Fig. 9-2). On binding the hormone, the soluble receptors change their conformation and gain the ability to bind to specific DNA sequences in the nucleus. The steroid hormone receptors are transported to the nucleus only after they bind hormone, but the retinoid receptors are in the nucleus and bind to DNA even without hormone present. They are both activated to start transcription when they bind hormone.

The homogeneous part of eqn. (3.43) is x(t) = F(t)x(t). (3.53)

The McGraw Hill Companies, 2010

To find out how many of an item a text object contains, get the count of the item. For example, use count of paragraphs in doc_process to return the number of paragraphs in doc_process.

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Let s change the current layer to Objects. 1. Pick Objects and pick the Set Current button. The Set Current button is the green check mark at the top of the palette. You can also make a layer current by doubleclicking the icon in the Status column next to the layer name.

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With the new era of Governance, Risk Management, and Compliance (GRC) firmly upon us, security and auditing excuses are quickly evaporating. As the custodians of data, IT professionals are being asked to protect personally identifiable information (PII), personal health information (PHI), and an assortment of other valuable data such as credit card numbers or bank account information used in electronic banking transactions. We must now comply with the cadre of new legal requirements: Sarbanes-Oxley (SOX), state privacy laws, the Payment Card Industry s Data Security Standard, EU privacy directives, Corporate Law Economic Reform Program Act (CLERP9), and Basel II to name just a few. In this emerging GRC and privacy era, these requirements are just that requirements. They are no longer optional and are now part of company business plans. They are not considered extra overhead, or a luxury item that is, if we have spare time, money, and computing cycles, then we ll audit. Some consider auditing a tax, but as with all taxes, they still have to be paid. An emerging view of auditing is now gaining popularity, however. From a GRC perspective, auditing provides an additional layer of oversight to existing access and physical controls. You can think of auditing as a safety net that catches things that fall through the protection controls. In these instances, while you cannot prevent a security compromise (because if you could have, you would have), you can detect them when they occur. This allows you to respond to and remediate any data breaches or other negative events. The timeliness of the detection and response is critical and crucial to preserving public image and setting up prevention techniques that will protect against future attacks.

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You re traveling to another dimension, a dimension not only of sight and sound, but of mind a journey into a wondrous land whose boundaries are that of imagination. The signpost up ahead: Fibonacci. All teasing aside, a number of extremely serious traders are devoted to the Fibonacci sequence, that mysterious indicator with a really cool name. Short-term traders primarily use it to identify key support and resistance areas. The support and resistance levels are based on the retracement of a previous move, either up or down. You ll have to read a book or take classes to fully understand Fibonacci, but I ll do my best to summarize it. A brilliant thirteenthcentury Italian mathematician, Leonardo Fibonacci, helped to promote a sequence of numbers that is the sum of the previous two

Notice that the right-handsidesof Eqs. (21.12) and (21.15) are identical,with the exception of the argumentof the third derivative.If the third derivativedoesnot vary appreciably over the interval in question,we can assumethat the right-handsidesare equal, and therefore,the left-handsidesshouldalso be equivalent,as in

In this example, you create a subroutine for trimming any leading spaces or trailing spaces off a string of text. As mentioned in 5, trimming off spaces is useful when you need to make sure that a string of text you use doesn t start or end with a space for example, to avoid layout problems in documents or errors in sorting. To create the subroutine, follow these steps:

80 percent of that one-rep-max weight. For example, if your one-rep max on the bench press is 200 pounds, 80 percent is 160.

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