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That s it, close the book, you ve done it OK, don t close the book there are details to examine, but take a moment to congratulate yourself Have a cookie Granted, the program you created is one of the simplest C# programs imaginable, but it is a complete C# program, and it can be used to examine many of the elements common to C# programs If your program didn t run as anticipated, don t panic If something is wrong in the code, Visual Studio will pop up a dialog box saying There were build errors Would you like to continue and run the last successful build In a program this simple, you most likely made what s called a syntax error, which is a term programmers use because they don t want to admit they made a typo, which is usually what happened.

Age is the most important determinant of the severity of rubella Postnatally acquired rubella is usually innocuous with up to 50% cases asymptomatic, whereas fetal rubella can be devastating In the postnatally acquired infection, fever and malaise, usually mild, accompanied by tender suboccipital adenitis, may precede the eruption by 1 week Mild coryza may be present Polyarticular arthritis occurs in about 25% of adult cases and involves the fingers, wrists, and knees Rarely

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mortality rate is 20%, but residual deficits are rare among the recovered The mechanism is unknown Other unusual complications of rubella include hemorrhagic manifestations due to thrombocytopenia and vascular damage, duodenal stenosis, and mild hepatitis

does chronic arthritis develop The polyarthritis usually subsides within 7 days but may persist for weeks Early posterior cervical and postauricular lymphadenopathy is very common Erythema of the palate and throat, sometimes patchy, may be noted A fine, pink maculopapular rash appears on the face, trunk, and extremities in rapid progression (2 3 days) and fades quickly, usually lasting 1 day in each area (Table 32 2) Rubella without rash may be at least as common as the exanthematous disease Diagnosis, when suspected because of disease in the community, requires serologic confirmation

Select No in this dialog and Visual Studio will open an error window at the bottom of the interface with a message that may or may not be helpful, depending on exactly what s wrong..

Live attenuated rubella virus vaccine should be given to all infants and to susceptible girls before the menarche When women are immunized, they should not be pregnant, and the absence of antibodies should be established (In the United States, about 80% of 20-year-old women are immune to rubella) Postpartum administration to susceptible female hospital employees is recommended, though many hospitals fail to comply It is recommended that women not become pregnant for at least 3 months after vaccine administration Nonetheless, there are no reports of congenital rubella syndrome after rubella immunization, and inadvertent immunization of a pregnant woman is not considered an indication for therapeutic abortion Arthritis is more marked after rubella vaccination than in native disease and appears to be immunologically mediated The association between chronic arthropathies and rubella vaccination is controversial MMR may be given in conjunction with diphtheria pertussis tetanus (DPT) boosters as adequate serologic responses are documented The administration of two or more doses appears to overcome an immunogenetic risk for vaccine failure in some vaccinees

Leukopenia may be present early and may be followed by an increase in plasma cells Virus isolation and serologic tests of immunity (rubella virus hemagglutination inhibition and fluorescent antibody tests) are available Definitive diagnosis is based on elevated IgM antibody, fourfold or greater rise in IgG antibody titers, or isolation of the virus False-positive IgM antibodies, however, are associated with Epstein-Barr virus, cytomegalovirus, parvovirus, and rheumatoid factor

When a pregnant woman is exposed to a possible case of rubella, an immediate hemagglutination-inhibiting rubella antibody level should be obtained, since fetal infection during the first trimester leads to congenital rubella in at least 80% of fetuses There is no reason for concern with positive tests since these indicate immunity If no antibodies are found, clinical observation and serologic follow-up are essential although an isolated IgM-positive test needs to be interpreted with caution because it does not necessarily imply acute infection Confirmation of rubella in the expectant mother raises the question of therapeutic abortion, an alternative to be considered in light of personal, religious, legal, and other factors The risk to the fetus is highest for maternal infection in the first trimester with deafness the primary complication in the second trimester

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